Fluorogenic DPP3 Assay Kit
Catalog #: 80203
Size: 96 reactions
DESCRIPTION: Dipeptidyl peptidase-3 (DPP3) is a serine exopeptidase that cleaves Xproline dipeptides from the N-terminus of polypeptides. DPP3 activity has been associated with endometrial and ovarian cancers. The Fluorogenic DPP3 Assay Kit is designed to measure DPP3 activity using purified DPP3 for screening or profiling applications. It comes in a convenient 96-well format, with purified DPP3 enzyme, DPP substrate, and DPP assay buffer for 100 enzyme reactions. The key to the Fluorogenic DPP3 Assay Kit is the specific, fluorogenic substrate. Using this kit, only one simple step on a microtiter plate is required for DPP3 reactions. The fluorometric substrate is incubated with a sample containing DPP3 enzyme to produce a fluorophore that can then be measured using a fluorescence reader.
APPLICATIONS: Great for studying enzyme kinetics and screening small molecular
inhibitors for drug discovery and HTS applications.
STORAGE: -20°C or -70°C.
1. Gevaert,K. et al., Proteomics 5 (14), 3589-3599 (2005)
2. Abramic,M. et al., Int. J. Biochem. Cell Biol. 36 (3), 434-446 (2004)