PDGF-BB (human, recombinant)
Catalog #: 90800-3

Size: 1000 µg

Description: Human recombinant PDGF-BB (GenBank Accession No. NM_002608) is a 24.3
kDa disulfide-linked homodimer of two B chains (218 total amino acids) expressed in an E.coli
expression system.

Source: E.coli

Stability: The lyophilized protein is stable for at least 2 years from date of receipt at -20°C.

Purity: >98% by SDS-PAGE and HPLC analysis.

Endotoxin Level: < 1EU per µg of PDGF-BB as determined by the LAL method.

Biological Activity: The ED50 as determined by the dose-dependent stimulation of BALB/c 3T3
cells proliferation is < 1.0 ng/ml.

References:
1. Early rise in serum VEGF and PDGF levels predisposes patients with a normal MBL2
genotype to restenosis after eversion endarterectomy Stroke 38 (8), 2247-2253 (2007)
2. Sorafenib inhibits imatinib-resistant KIT and platelet-derived growth factor receptor beta
gatekeeper mutants Clin. Cancer Res. 13 (11), 3363-3369 (2007)